Anderson Cooper’s daytime show to end after two seasons

























NEW YORK (Reuters) – Anderson Cooper‘s venture into daytime is coming to an end after just two seasons after failing to find an audience in the crowded daytime talk show market.


Warner Bros Television, which syndicates “Anderson”, said on Monday the show will not be renewed after the current season ends in the summer of 2013.





















“The series will not be coming back for a third season in a marketplace that has become difficult to break through,” Warner Bros said in a statement.


The CNN anchor launched “Anderson,” subsequently retitled “Anderson Live,” in September 2011. But the show has struggled in the ratings despite retooling in the face of competition from veteran daytime hosts such as Ellen DeGeneres, and newcomers such as Katie Couric and “Survivor” host Jeff Probst.


“Anderson Live,” is attracting an average audience of about 1.4 million viewers, compared with around 4 million for “Dr. Phil” and about 2.3 million for “Katie,” according to TV ratings data.


Cooper issued a statement on Monday saying, “I am very proud of the work that our terrific staff has put into launching and sustaining our show for two seasons,” and added that he looked forward “to doing more great shows this season … I’m sorry that we won’t be continuing.”


TV stations carrying the show were first informed on Friday that the producers were not seeking renewal for another season.


Cooper, 45, and the winner of multiple Emmy award and a Peabody Award, continues as host of the CNN news program “Anderson Cooper 360” and has hosted the network’s New Year’s Eve special from Times Square for several years running.


Warner Bros is owned by Time Warner Inc.


(Reporting by Chris Michaud, editing by Jill Serjeant and Marguerita Choy)


TV News Headlines – Yahoo! News



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Lilly trials boost amyloid-protein link to Alzheimer’s-analysis

























(Reuters) – Levels of a protein believed to be a main cause of Alzheimer’s disease rose in the blood of patients treated with Eli Lilly‘s experimental drug in late-stage trials, suggesting the protein, beta amyloid, was removed from the brain as intended, researchers said on Monday.


Lilly in August disclosed that its drug solanezumab did not significantly arrest progression of the memory-robbing disease in the pair of Phase III studies, which tested patients with mild to moderate symptoms of Alzheimer’s.





















But the company later said an analysis of combined data from the two trials suggested the drug significantly slowed cognitive decline in patients with only mild symptoms, although it did not slow the decline of their physical function.


The finding from the pooled trial data helped restore some faith in the closely followed Lilly drug – that it might hold promise in treating patients who have not yet developed symptoms or who are in the very earliest stages of the disease.


Researchers on Monday, attending the Clinical Trials in Alzheimer’s Disease (CTAD) annual scientific meeting in Monaco, said an independent analysis of the trial data suggested that beta amyloid was removed from the brain into the bloodstream of patients taking solanezumab.


“The results support continued interest in amyloid as a therapeutic target in Alzheimer’s disease research,” CTAD said in a release.


Rachelle Doody, an Alzheimer’s disease researcher from Baylor School of Medicine who led the analysis, said the removal of amyloid from the brain into the blood – and slight cognitive improvement seen – lend credence to amyloid as a culprit in the disease.


“The beta amyloid biomarker results in the trial support the small, yet significant cognitive benefit” seen with the anti-amyloid approach, Doody said.


Researchers said the studies support the earlier use of drugs like solanezumab, which target toxic amyloid plaques in the brain, to prevent symptoms of the disease. One such prevention study is slated to begin next year at Washington University in St. Louis, and includes use of the Lilly drug.


Researchers in Monaco said no changes were seen in any other biomarkers – meaning proteins or tissue changes believed associated with the disease – including another suspected leading culprit protein called tau.


Alzheimer’s is a progressive and ultimately fatal disease affecting an estimated 35 million people worldwide, CTAD said, adding the number is expected to exceed 115 million if nothing is done to slow or prevent the disease.


(Reporting By Ransdell Pierson; Editing by Steve Orlofsky)


Diseases/Conditions News Headlines – Yahoo! News



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Hurricane Sandy begins battering the East Coast

NEW YORK/REHOBOTH BEACH, Delaware (Reuters) - Hurricane Sandy, one of the biggest storms ever to hit the United States, battered the densely populated East Coast on Monday, shutting down transportation, forcing evacuations in flood-prone areas and interrupting the presidential election campaign.


Fierce winds and flooding were expected along hundreds of miles of Atlantic coast and heavy snows were forecast farther inland at higher elevations when the center of the storm moves ashore Monday evening near Atlantic City, New Jersey.


U.S. stock markets were closed for the first time since the attacks of September 11, 2001, and will remain shut on Tuesday. The government in Washington was closed and school was canceled up and down the East Coast.


Nearly 700,000 customers were without power by midday and millions more could lose electricity. One disaster forecasting company predicted economic losses could ultimately reach $20 billion, only half of it insured.


"This is going to be a big and powerful storm and all across the Eastern Seaboard I think everybody is taking the appropriate preparations," President Barack Obama said at the White House.


State governors from Virginia to Massachusetts warned of the acute danger from the storm for the 60 million residents in its path. Ten states have declared a state of emergency.


"There will undoubtedly be some deaths that are caused by the intensity of this storm, by the floods, by the tidal surge, by the waves. The more responsibly citizens act, the fewer people will die," Maryland Governor Martin O'Malley told reporters.


Forecasters said Sandy could be the largest storm to hit the mainland in U.S. history.


Off North Carolina, the U.S. Coast Guard rescued 14 of the 16 crew members who abandoned the replica tall ship HMS Bounty, using helicopters to lift them from life rafts. The Coast Guard continued to search for two missing crew members.


In New York, a crane atop a building on 57th Street in Manhattan had partially collapsed, leaving it dangling high above the street. Police said they were closing the area to pedestrians.


GAINING SPEED


The storm interrupted the presidential campaign with eight days to go before the election.


Obama canceled a campaign event in Florida on Monday so he could return to Washington and monitor the government response to the storm. Republican presidential candidate Mitt Romney canceled stops Monday night and Tuesday.


Sandy picked up speed as it raced northwest toward the U.S. coast at 28 miles per hour (45 km per hour) on Monday afternoon, with top sustained winds at 90 mph, the U.S. National Hurricane Center said.


At 2 p.m. (1800 GMT) the center of the storm was about 110 miles southeast of Atlantic City, New Jersey, or 175 miles south-southeast of New York City. Hurricane-force winds were already being recorded on the New Jersey coast.


"The center of Sandy is expected to make landfall along or just south of the southern New Jersey coast by early evening," NHC forecasters said, adding they expected little change in strength before then.


Forecasters said Sandy was a rare, hybrid "super storm" created by an Arctic jet stream wrapping itself around a tropical storm.

 

The combination of those two storms would have been bad enough, but meteorologists said there was a third storm at play - a system coming down from Canada that would effectively trap the hurricane-nor'easter combo and hold it in place.


Moreover, the storm was coming ashore at high tide, which was pulled even higher by a full moon.


While Sandy does not pack the punch of Hurricane Katrina, which devastated New Orleans in 2005, it has been gathering strength. It killed 66 people in the Caribbean last week before pounding U.S. coastal areas as it moved north.


'SOMETHING LIKE KATRINA'


In Fairfield, a Connecticut coastal town and major commuter point into Manhattan, police cruisers blocked the main road leading to the beaches and yellow police tape cordoned off side entrances. Beach pavilions were boarded up with plywood, and gusts of wind rocked parked cars.


"People are definitely not taking this seriously enough," police officer Tiffany Barrett, 38, said. "Our worst fear is something like Katrina and we can't get to people."


Further south, several feet of water flooded streets in Rehoboth Beach, Delaware. Police knocked on doors, reminding people there was a mandatory evacuation. While the police took names, they allowed residents to stay at their own risk.


Besides rain, the storms could cause up to 3 feet (1 meter) of snowfall in the Appalachian Mountains from West Virginia to Kentucky. Some people in that part of the country did not have to go to work because of the storm and used the time to vote.


At the Berkeley County Courthouse in Martinsburg, West Virginia, early voting for the November 6 elections was going ahead despite the bad weather, with some 600 people casting ballots by about 1:45 p.m. (1745 GMT)


"More (people) came out today than what I anticipated but a lot of people are off work," Bonnie Woodfall, chief deputy for voter registration, said after fielding a flurry of calls about whether the polls should stay open. "It's neat."


'RECORD-SIZED OUTAGES'


New York and other cities closed their transit systems and schools, ordering mass evacuations from low-lying areas ahead of a storm surge that could reach as high as 11 feet.


By early Monday, water was already topping the seawall in Manhattan's Battery Park City, one of the areas ordered evacuated by Mayor Michael Bloomberg.


He ordered 375,000 New Yorkers to evacuate and told those who remained to leave immediately. "Conditions are deteriorating rapidly and the window for you getting out safely is closing."


New York electric utility Con Edison said it expected "record-size outages," with nearly 35,000 customers in lower Manhattan and Brooklyn likely to be impacted. The company is facing both falling trees knocking down power lines from above and flood waters swamping underground systems from below.


All U.S. stock markets were closed on Monday and will remain shut on Tuesday, with a plan to re-open on Wednesday that depends on conditions after the storm passes.


The United Nations, Broadway theaters and New Jersey casinos were forced to close and more than two-thirds of East Coast oil refining capacity was in the process of shutting down.


Airlines canceled flights, bridges and tunnels closed, and national passenger rail operator Amtrak suspended nearly all service on the East Coast. The U.S. government told non-emergency workers in Washington, D.C., to stay home.


Up and down the coast, worried residents in the hurricane's path packed stores, searching for generators, flashlights, batteries, food and other emergency supplies.


Johnny Lopez, an owner of Best Buy Wines and Liquors in Brooklyn, said he plans - "God help us!" - to stay open all day on Monday and Tuesday.


"Crazy busy yesterday," he said. "It was like Thanksgiving."


(Additional reporting by Greg Roumeliotis, Edith Honan, Janet McGurty and Martinne Geller in New York, Barbara Goldberg in New Jersey, Mary Ellen Clark and Lynnley Browning in Connecticut, Daniel Lovering in Boston, Ian Simpson in West Virginia, Susan Heavey in Washington, Jane Sutton in Miami; Writing by Paul Thomasch and Ben Berkowitz; Editing by Eric Beech)

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Pole gets 30 years for killing 6 on Channel Island

























LONDON (AP) — A Polish builder who killed six people, including his wife and children, on the British Channel Island of Jersey has been sentenced to 30 years in prison.


Damian Rzeszowski, 31, carried out the knife attack in August 2011 at his home. He was said to have become depressed after his wife admitted to an affair.





















Rzeszowski was convicted of six counts of manslaughter but cleared of murder. On Monday, Judge Michael Birt sentenced him to 30 years in jail for each victim, but the sentences are to run concurrently.


Rzeszowski’s victims were his wife Izabela Rzeszowska, 30; 5-year-old daughter, Kinga; 2-year-old son, Kacper; father-in-law, Marek Gartska, 56; his wife’s friend Marta De La Haye, 34; and her 5-year-old daughter, Julia.


Europe News Headlines – Yahoo! News



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Google unveils first 10-inch Nexus tablet

SAN FRANCISCO (Reuters) - Google Inc unveiled a larger version of its Nexus-branded tablet computer on Monday, and updated its mobile gadget and online content offerings as competition with Apple Inc, Amazon.com Inc and Microsoft Corp heats up ahead of the holiday sales season.


The device follows a spate of new product launches by the technology leaders in recent weeks, including Apple's iPad Mini last week and software-maker Microsoft's first-ever home-built tablet, the Surface.


Google, the world's No.1 Internet search engine, has pushed deeper into the hardware business at a time when consumers are increasingly accessing the Web on mobile devices.


Google's new Nexus 10, made in partnership with consumer electronics company Samsung Electronics Co, is the first 10-inch tablet to come to market under Google's Nexus brand. The device, with prices starting at $299, will be available on November 13 in the United States and seven other countries, Google said in its official blog on Monday.


Google was scheduled to introduce the device at a media event in New York on Monday, but was forced to cancel because of Hurricane Sandy.


Google also said it was expanding its online movie and music retail businesses to several countries in Europe.


And the company introduced an improvement to its online-music storage service. The new "matching" feature scans songs in a consumer's music collection and automatically creates an online or "cloud-based" library of the same tracks which consumers can access from any device or computer.


Google said the music matching feature, which only works with tracks that are part of the Google Play store's music catalog, will be available in Europe on November 13 and in the United States soon after.


Google also updated its smaller, Nexus 7 tablet released earlier this year. It increased the storage on the $199 version of the device to 16GB from 8GB, and introduced a new $299 version of the Nexus 7 with a cellular data service option. Google also unveiled a new Nexus 4 smartphone, made in partnership with LG Electronics, that features a quad-core processor and a 4.7-inch display.


(Reporting by Alexei Oreskovic; Editing by Richard Chang)


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Broadway takes few chances with superstorm coming

























NEW YORK (AP) — Broadway took the threat of the mammoth storm seriously, with theater owners canceling all Sunday evening and Monday performances of shows like “The Book of Mormon” ”Once” and “Mama Mia!” long before a drop of rain fell in Times Square.


“The safety and security of theatregoers and employees is everyone’s primary concern,” said Charlotte St. Martin, executive director of The Broadway League, which represents producers.





















Forecasts called for rain late Sunday or early Monday, and subway and public transportation service is to be halted Sunday evening, potentially stranding theatergoers. Refunds will be made available from the point of purchase.


Off-Broadway shows including “Stomp,” ”Bad Jews” and “Golden Child” were also canceled Sunday night. Most matinees on and off Broadway stayed open. Mondays are usually very light on Broadway, with most shows having that as their day off.


Some Broadway shows had no evening shows scheduled Sunday, including “Cyrano de Bergerac,” ”Annie,” ”Chaplin,” ”Enemy of the People,” ”Once,” ”Jersey Boys” and “Nice Work If You Can Get It.”


It was the most disruptive storm for the theater community since the threat of Hurricane Irene in late August 2011 prompted producers to cancel matinee and evening performances on Saturday and Sunday. While that hurricane mostly fizzled over New York, every show lost money because they were mostly limited to five or six performances that week.


Entertainment News Headlines – Yahoo! News



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New test to improve HIV diagnosis in poor countries

























LONDON (Reuters) – Scientists have come up with a test for the virus that causes AIDS that is ten times more sensitive and a fraction of the cost of existing methods, offering the promise of better diagnosis and treatment in the developing world.


The test uses nanotechnology to give a result that can be seen with the naked eye by turning a sample red or blue, according to research from scientists at Imperial College in London published in the journal Nature Nanotechnology.





















“Our approach affords for improved sensitivity, does not require sophisticated instrumentation and it is ten times cheaper,” Molly Stevens, who led the research, told Reuters.


Simple and quick HIV tests that analyze saliva already exist but they can only pick up the virus when it reaches relatively high concentrations in the body.


“We would be able to detect infection even in those cases where previous methods, such as the saliva test, were rendering a ‘false negative’ because the viral load was too low to be detected,” she said.


The test could also be reconfigured to detect other diseases, such as sepsis, Leishmaniasis, Tuberculosis and malaria, Stevens said.


Testing is not only crucial in picking up the HIV virus early but also for monitoring the effectiveness of treatments.


“Unfortunately, the existing gold standard detection methods can be too expensive to be implemented in parts of the world where resources are scarce,” Stevens said.


According to 2010 data from the World Health Organisation, about 23 million people living with HIV are in Sub-Saharan Africa out of a worldwide total of 34 million.


The virus is also spreading faster and killing more people in this part of the world. Sub-Saharan Arica accounted for 1.9 million new cases out of a global total of 2.7 million in the same year, and 1.2 million out of the 1.8 million deaths.


The new sensor works by testing serum, a clear watery fluid derived from blood samples, in a disposable container for the presence of an HIV biomarker called p24.


If p24 is present, even in minute concentrations, it causes the tiny gold nanoparticles to clump together in an irregular pattern that turns the solution blue. A negative result separates them into ball shapes that generate a red color.


The researchers also used the test to pick up the biomarker for Prostate Cancer called Prostate Specific Antigen, which was the target of previous work that Stevens did with collaborators at University of Vigo in Spain.


That sensor used tiny gold stars laden with antibodies that latched onto the marker in a sample and produced a silver coating that could be detected with microscopes.


Stevens and her collaborator on the new test, Roberto de la Rica, said they plan to approach not-for-profit global health organizations to help them manufacture and distribute the new sensor in low income countries.


(Editing by Jason Webb)


Health News Headlines – Yahoo! News



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Sandy: East Coast braces for epic hurricane, ‘life-threatening’ storm surge

Waves crash into a pier in Nags Head, N.C., Oct. 27, 2012. (Gerry Broome/AP)


[UPDATED: 3:00 p.m. ET]


"Superstorm." "The Perfect Storm." "Frankenstorm."


Whatever you want to call it, the East Coast is bracing for Hurricane Sandy, a "rare hybrid storm" that is expected to bring a life-threatening storm surge to the mid-Atlantic coast, Long Island Sound and New York harbor, forecasters say, with winds expected to be at or near hurricane force when it makes landfall sometime on Monday.


According to the National Hurricane Center, the Category 1 hurricane was centered about 270 miles southeast of Cape Hatteras, N.C., and 575 miles south of New York City early Sunday, carrying maximum sustained winds of 75 mph and moving northeast at 14 mph.


[Slideshow: Latest photos from Hurricane Sandy]


New York Mayor Michael Bloomberg ordered the immediate, mandatory evacuation for low-lying coastal areas, including Coney Island, the Rockaways, Brighton Beach, Red Hook and some parts of lower Manhattan.


"If you don't evacuate, you're not just putting your own life at risk," Mayor Bloomberg said at a news conference Sunday. "You're endangering first responders who may have to rescue you."


New Jersey Governor Chris Christie's message for residents was a bit more blunt. "Don't be stupid," Christie said Sunday afternoon, announcing the suspension of the state's transit system beginning at 12:01 a.m. Monday.


Earlier, New York Governor Andrew Cuomo announced the suspension of all MTA service--including subways, buses, Long Island Railroad and Metro North--beginning at 7 p.m. Sunday. New York City Public Schools will be closed on Monday, the mayor said. City offices and the New York Stock Exchange, however, will be open for business.


[Related: Superstorm could impact 60 million]


Sandy is expected to continue on a parallel path along the mid-Atlantic coast later Sunday before making a sharp turn toward the northwest and southern New Jersey coastline on Monday--with the Jersey Shore and New York City in its projected path.


But the path is not necessarily the problem.


"Don't get fixated on a particular track," the Associated Press said. "Wherever it hits, the rare behemoth storm inexorably gathering in the eastern U.S. will afflict a third of the country with sheets of rain, high winds and heavy snow."


(Weather.com)


A tropical storm warning has been issued between Cape Fear to Duck, N.C., while hurricane watches and high-wind warnings are in effect from the Carolinas to New England. The hurricane-force winds extend 175 miles from the epicenter of the storm, while tropical storm-force winds extend 520 miles--making Sandy one of the biggest storms to ever hit the East Coast.


"We're looking at impact of greater than 50 to 60 million people," Louis Uccellini, head of environmental prediction for the National Oceanic and Atmospheric Administration, told the Associated Press.


"The size of this alone, affecting a heavily populated area, is going to be history making," Jeff Masters wrote on the Weather Underground blog.


[Also read: Big storm scrambles presidential race schedules]


"I can be as cynical as anyone," Christie said on Saturday, announcing a state of emergency. "But when the storm comes, if it's as bad as they're predicting, you're going to wish you weren't as cynical as you otherwise might have been."


Meanwhile, emergency evacuations were being mulled by state officials in Connecticut, Massachusetts, Vermont, New Hampshire and even Maine.


In Virginia, Governor Bob McDonnell said 20,000 homes there had already reported power outages.


"This is not a coastal threat alone," said Craig Fugate, director of the Federal Emergency Management Agency, said during a media briefing early Sunday. "This is a very large area."


Forecasters also fear the combination of storm surge, high tide and heavy rain--between 3 and 12 inches in some areas--could be life-threatening for coastal residents.


According to the National Hurricane Center summary, coastal water levels could rise anywhere between 1 and 12 feet from North Carolina to Cape Cod, depending on the timing of the "peak surge." A surge of 6 to 11 feet is forecast for Long Island Sound and Raritan Bay, including New York Harbor.


The storm surge in New York Harbor during Hurricane Irene in September 2011, forecasters noted, was four feet.


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Ukraine’s opposition doing well in election

























KIEV, Ukraine (AP) —


Ukraine’s opposition parties performed strongly in Sunday’s parliamentary vote, according to an exit poll, but President Viktor Yanukovych‘s party could still retain control of the legislature as its members are likely to sweep individual races across the country.





















The West is paying close attention to the conduct of the vote in the strategic ex-Soviet state, which lies between Russia and the European Union, and serves as a key conduit for transit of Russian energy supplies to many EU countries. An election deemed unfair would likely turn Ukraine further away from the West and toward Moscow.


Opposition parties alleged widespread violations on election day, such as vote-buying and a suspiciously high amount of home voting, but a local election monitor said those violations were isolated. Authorities insisted the election was honest and democratic.


The Fatherland party, led by the jailed charismatic former Prime Minister Yulia Tymoshenko, the Udar (Punch) of world boxing champion Vitali Klitschko and a nationalist party together received more than 50 percent of the vote on party lists, outnumbering Yanukovych’s Party of Regions and its traditional ally, the Communist Party.


Both Yanukovych’s and Tymoshenko’s parties claimed victory, saying the election showed the voters trust them to lead the country.


However, only half of the parliament’s 450 seats are split proportionately between the winning parties. The other half is filled by the winners of single-mandate races, where Yanukovych loyalists are expected to make a strong showing. In the election, each voter had two ballots, one with party names and one with the name of candidates in specific constituencies. No exit poll numbers were available for the individual races.


With Yanukovych under fire over the jailing of his top rival, Tymoshenko; rampant corruption and slow reforms, the opposition made a strong showing.


Tymoshenko’s Fatherland party is poised to get about 25 percent of the proportional vote, the Udar (Punch) led by world boxing champion Vitali Klitschko is set to get around 15 percent and the nationalist Svoboda (Freedom) party receives some 12 percent. The Party of Regions polled 28 percent and the Communists nearly 12 percent.


If the three opposition groups unite, they could get 127 parliament seats versus 98 seats gained by the Regions and Communists. The distribution of the remaining 225 seats is expected to be clear Monday.


Opposition forces hope to garner enough parliament seats to weaken Yanukovych’s power and undo the damage they say he has done: the jailing of Tymoshenko and her top allies, the concentration of power in the hands of the president, the snubbing of the Ukrainian language in favor of Russian, waning media freedoms, a deteriorating business climate and growing corruption.


The strong showing by the far-right Svoboda (Freedom) party which campaigns for the defense of the Ukrainian language and culture but is also infamous for xenophobic and anti-Semitic rhetoric emerged as a surprise and showed the widespread disappointment and anger with the ruling party.


It remains to be seen whether Tymoshenko’s group, Klitschko’s party and Svoboda can forge a strong alliance and challenge Yanukovych.


The election tainted by Tymoshenko’s jailing on charges of abuse of office has also been compromised by the creation of fake opposition parties, campaigns by politically unskilled celebrities, and the use of state resources and greater access to television by Yanukovych’s party.


___


Yuras Karmanau in Kiev contributed to this report.


Europe News Headlines – Yahoo! News



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SAP eyes "long" period of high sales growth: report

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